Syncope and seizures following human papillomavirus vaccination: a retrospective case series.

Human papillomavirus vaccine in boys: background rates of potential adverse events.

OBJECTIVES To determine background rates of potential adverse events following immunisation (AEFI) before expansion of the quadrivalent human papillomavirus (4vHPV) vaccination program to adolescent boys. DESIGN, PATIENTS AND SETTING Retrospective analysis of hospital discharge data obtained from the Victorian Admitted Episodes Dataset and emergency department visit data obtained from the Vic...

1050Evaluation of syncope and related events following vaccination with quadrivalent human papillomavirus vaccine (2006-2013)

Death after Quadrivalent Human Papillomavirus (HPV) Vaccination: Causal or Coincidental?

Background: The proper understanding of a true risk from vaccines is crucial for avoiding unnecessary adverse reactions (ADRs). However, to this date no solid tests or criteria have been established to determine whether adverse events are causally linked to vaccinations. Objectives: This research was carried out to determine whether or not some serious autoimmune and neurological ADRs following...

Postural tachycardia syndrome following human papillomavirus vaccination.

BACKGROUND AND PURPOSE Postural tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system that may have an autoimmune etiology. METHODS Six patients who developed new onset POTS 6 days to 2 months following human papillomavirus vaccination are reported. RESULTS Three patients also had neurocardiogenic syncope, and three patients were diagnosed with possible sma...

Monitoring the safety of quadrivalent human papillomavirus vaccine: findings from the Vaccine Safety Datalink.

BACKGROUND In 7 large managed care organizations (MCOs), we performed a post-licensure safety assessment of quadrivalent human papillomavirus vaccine (HPV4) among 9-26 year-old female vaccine recipients between August 2006 and October 2009. METHODS Sequential analyses were conducted weekly to detect associations between HPV4 exposure and pre-specified outcomes. The pre-specified outcomes iden...